| Cardiac dysrhythmias and heart rate changes at induction of anaesthesia: a comparison of two intravenous anticholinergics. | |
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MedLine Citation:
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PMID: 6375235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Glycopyrrolate, 0.2 mg, or atropine, 0.6 mg, was administered intravenously together with methohexitone for the induction of anaesthesia in unpremedicated patients. The use of atropine, compared with glycopyrrolate, was associated with a greater rise in heart rate, a greater number of patients whose heart rates doubled, and a higher incidence of dysrhythmias. Glycopyrrolate is recommended for use as an intravenous anticholinergic agent, particularly in patients with cardiovascular impairment. |
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Authors:
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J Greenan |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Acta anaesthesiologica Scandinavica Volume: 28 ISSN: 0001-5172 ISO Abbreviation: Acta Anaesthesiol Scand Publication Date: 1984 Apr |
Date Detail:
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Created Date: 1984-07-10 Completed Date: 1984-07-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370270 Medline TA: Acta Anaesthesiol Scand Country: DENMARK |
Other Details:
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Languages: eng Pagination: 182-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Anesthesia, Intravenous* Arrhythmias, Cardiac / chemically induced* Atropine / administration & dosage, adverse effects Clinical Trials as Topic Double-Blind Method Electrocardiography Female Glycopyrrolate / administration & dosage, adverse effects Heart Rate / drug effects* Humans Injections, Intravenous Male Methohexital / administration & dosage, adverse effects Middle Aged Parasympatholytics / administration & dosage, adverse effects* Random Allocation |
| Chemical | |
Reg. No./Substance:
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0/Parasympatholytics; 18652-93-2/Methohexital; 51-55-8/Atropine; 596-51-0/Glycopyrrolate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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