Document Detail


Cardiac dysfunction in patients seropositive for the human immunodeficiency virus.
MedLine Citation:
PMID:  1771874     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To confirm the presence of cardiac dysfunction in a group of patients seropositive for the human immunodeficiency virus with either dyspnea on exertion or a reduced anaerobic threshold, 9 patients with no history of opportunistic infection underwent exercise right-sided heart catheterization. When compared with 13 control patients previously exercised in the same manner, the patients showed elevated exercise pulmonary capillary wedge pressure (14.6 +/- 3.3 mm of mercury versus 9.9 +/- 3.3 mm of mercury; P less than .005) and right atrial pressure (10.1 +/- 2.1 mm of mercury versus 4.7 +/- 3.2 mm of mercury; P less than .001) at a similar exercise oxygen consumption and cardiac index. Of the 9 patients, 8 had at least 1 catheterization value outside the 95% confidence limits for the control group and 4 patients had multiple abnormalities. Values for blood CD4 lymphocytes were 0.2 x 10(9) per liter or more for 7 of the 9. One patient underwent endomyocardial biopsy with findings consistent with a cardiomyopathy. We conclude that cardiac disease may occur at any immunologic stage of human immunodeficiency virus infection. These observations suggest an effect of this disease on the heart.
Authors:
J E Johnson; D M Slife; G T Anders; S R Bailey; H M Blanton; C K McAllister; R D Latham
Related Documents :
16495754 - Exercise training attenuates acute doxorubicin-induced cardiac dysfunction.
24278894 - Treadmill exercise alleviates post-traumatic stress disorder-induced impairment of spat...
8779874 - Augmented baroreflex heart rate gain after moderate-intensity, dynamic exercise.
12882494 - Cardiac toxicity caused by achyranthes aspera.
3676034 - Detection of exercise induced changes in left ventricular performance by doppler echoca...
2091594 - Reliability of surface electromyography of the masseteric and anterior temporal areas.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Western journal of medicine     Volume:  155     ISSN:  0093-0415     ISO Abbreviation:  West. J. Med.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-02-26     Completed Date:  1992-02-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0410504     Medline TA:  West J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  373-9     Citation Subset:  AIM; IM; X    
Affiliation:
Pulmonary Disease/Critical Care Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Electrocardiography
Exercise Test
HIV Seropositivity / complications,  pathology,  physiopathology*
Heart / physiopathology*
Heart Catheterization
Heart Diseases / complications
Hemodynamics
Humans
Male
Myocardium / pathology
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Helmet use improves outcomes after motorcycle accidents.
Next Document:  Patterns of primary care of patients infected with human immunodeficiency virus.