Document Detail

Cardiac damage produced by transchest damped sine wave shocks.
MedLine Citation:
PMID:  634186     Owner:  NLM     Status:  MEDLINE    
High-energy transchest damped wave sine defibrillation shocks have been shown to produce cardiac damage when applied in rapid sequence. However, there are no reports as to whether single, threshold-intensity shocks produce damage. In this study, nonfibrillating dogs were subjected either to a single, threshold-intensity (1 A/kg) shock, or to a series of 6 shocks with high intensity (3 to 4.8 A/kg). Electrodes of 8 cm diameter were used to apply the shock through the chest wall. Dogs receiving shocks of adequate (but not excessive) strength to defibrillate showed no cardiac damage, although they exhibited transient ventricular arrhythmias after the shock was applied. All dogs receiving the higher intensity, multiple shocks showed gross and microscopic evidence of cardiac damage. Ventricular lesions were observed in both right and left ventricular free walls and were sometimes transmural in extent. ECG analysis of the records from the dogs receiving multiple, high-intensity shocks showed second and third degree A-V block, ventricular ectopic beats, ventricular tachycardia, S-T segment changes, and T-wave inversion. Although multiple, high-energy, high-current defibrillation shocks produce permanent cardiac damage in dogs, threshold shocks do not produce morphologic changes.
W A Tacker; J S Davis; J T Lie; J L Titus; L A Geddes
Related Documents :
12556676 - Cardiogenic shock: a summary of the randomized shock trial.
18556106 - Recurrent ventricular fibrillation during advanced life support care of patients with p...
16695956 - Studies in clinical shock and hypotension: vi. relationship between left and right vent...
17646586 - A decade of short-term outcomes in post cardiac surgery ventricular assist device impla...
2400256 - Artificial mitral valve chordae: experimental and clinical experience.
10608046 - Glucose-insulin-potassium does not reduce myocardial infarct size in an ischemic/reperf...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical instrumentation     Volume:  12     ISSN:  0090-6689     ISO Abbreviation:  Med Instrum     Publication Date:    1978 Jan-Feb
Date Detail:
Created Date:  1978-05-17     Completed Date:  1978-05-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0361136     Medline TA:  Med Instrum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arrhythmias, Cardiac / etiology
Electric Countershock / adverse effects*
Heart Diseases / etiology*,  pathology
Myocardium / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of transthoracic square-wave defibrillation experience in the dog and calf.
Next Document:  The effect of shock separation time on multiple-shock defibrillation.