Document Detail

Cardiac consequences of the systemic lupus erythematosus therapy with corticosteroids morphological study.
MedLine Citation:
PMID:  14974235     Owner:  NLM     Status:  MEDLINE    
It is presented the case of a fifty years old women, diagnosed 3 years ago with systemic lupus erythematosus, under therapy with prednisone and cyclophosphamid therapy. She was admitted in our hospital for right decompensated heart disease and the presence of an apical right ventricular mass occluding part of the right ventricular cavity. The endomyocardial biopsy was made to clearify the nature of this mass. After processing the specimen, the histological study evidenciated an organizing apical thrombotic mass formed in a large right ventricular cavity in conditions of pulmonary hypertention. There are presented data concerning the adverse effects of the systemic lupus erythematosus drug therapy, as well. In these circumstances, we demonstrated histologically, that both conditions could alter the heart morphology.
Cătălina Arsenescu; Doina Butcovan; M Rotar; G I Georgescu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i     Volume:  106     ISSN:  0048-7848     ISO Abbreviation:  Rev Med Chir Soc Med Nat Iasi     Publication Date:    2002 Oct-Dec
Date Detail:
Created Date:  2004-02-20     Completed Date:  2004-04-28     Revised Date:  2011-01-13    
Medline Journal Info:
Nlm Unique ID:  0413735     Medline TA:  Rev Med Chir Soc Med Nat Iasi     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  812-6     Citation Subset:  IM    
School of Medicine, Medical Cardiology-Cardiology Center, University of Medicine and Pharmacy Gr.T. Popa, Iaşi.
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MeSH Terms
Adrenal Cortex Hormones / adverse effects*
Endocardium / pathology
Endomyocardial Fibrosis / chemically induced*,  pathology
Lupus Erythematosus, Systemic / drug therapy*,  pathology
Middle Aged
Reg. No./Substance:
0/Adrenal Cortex Hormones

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