Document Detail


Cardiac consequences of hypertension in hemodialysis patients.
MedLine Citation:
PMID:  15250922     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hypertension in end-stage renal disease (ESRD) is an important risk factor for left ventricular hypertrophy (LVH), cardiac failure, coronary artery disease (CAD), and arrhythmia. LVH is generally considered an integrator of the long-term effects of hypertension and other cardiovascular (CV) risk factors and represents the strongest predictor of adverse CV outcomes in ESRD patients. The risk of heart failure is higher in patients with a history of hypertensive renal disease than in those with other diagnoses. Both coronary heart disease (CHD) and LVH predict congestive heart failure, which is often the ultimate cause of death in patients with cardiac ischemia or LVH. A history of long-standing hypertension is associated with ischemic heart disease both in cross-sectional and prospective studies in ESRD. Atrial fibrillation and ventricular arrhythmias are highly prevalent in dialysis patients and are implicated in mortality and sudden death in this population. Despite the lack of evidence from randomized controlled trials, it appears reasonable that interventions aimed at curbing the high CV mortality of ESRD should be targeted to both hypertension and LVH.
Authors:
Carmine Zoccali; Francesco Antonio Benedetto; Giovanni Tripepi; Francesca Mallamaci
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in dialysis     Volume:  17     ISSN:  0894-0959     ISO Abbreviation:  Semin Dial     Publication Date:    2004 Jul-Aug
Date Detail:
Created Date:  2004-07-14     Completed Date:  2004-11-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8911629     Medline TA:  Semin Dial     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-303     Citation Subset:  IM    
Affiliation:
Istituto di Biomedicina-Epidemiologia Clinica e Fisiopatologia delle malattie Renali e dell'Ipertensione Arteriosa e Unità Operativa di Nefrologia, Dialisi e Trapianto Renale, Ospedali Riuniti, Reggio Calabria, Italy. carmine.zoccali@tin.it
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / etiology,  physiopathology
Coronary Disease / etiology,  physiopathology
Heart Diseases / etiology*
Heart Failure / etiology,  physiopathology
Humans
Hypertension / complications*,  physiopathology
Hypertrophy, Left Ventricular / etiology,  physiopathology
Kidney Failure, Chronic / complications,  physiopathology
Renal Dialysis*

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