| Cardiac complication from use of cocaine and phenylephrine in nasal septoplasty. | |
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MedLine Citation:
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PMID: 7772323 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cocaine hydrochloride is widely used as a topical anesthetic for otolaryngologic surgery. Cardiovascular complications, including myocardial injury, are well-documented side effects of illicit cocaine use. We describe a 23-year-old woman without coronary artery disease who had an acute non-Q-wave myocardial infarction and stunned myocardium after receiving topical phenylephrine hydrochloride and cocaine anesthesia for elective nasal septoplasty. These cases are rare; however, we hope to heighten the awareness of the potential lethal complications of using cocaine, phenylephrine, or the combination of both as topical anesthetics in otolaryngologic practice. |
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Authors:
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M Ashchi; H P Wiedemann; K B James |
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1819973 - Medical causes and effects of cocaine abuse. 3804323 - Cocaine and the heart. 12511533 - Echocardiographic wall motion abnormalities in hypertensive patients with electrocardio... |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Archives of otolaryngology--head & neck surgery Volume: 121 ISSN: 0886-4470 ISO Abbreviation: Arch. Otolaryngol. Head Neck Surg. Publication Date: 1995 Jun |
Date Detail:
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Created Date: 1995-07-07 Completed Date: 1995-07-07 Revised Date: 2006-03-28 |
Medline Journal Info:
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Nlm Unique ID: 8603209 Medline TA: Arch Otolaryngol Head Neck Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 681-4 Citation Subset: AIM; IM |
Affiliation:
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Mount Sinai Medical Center/MetroHealth Medical Center, Cleveland, Ohio, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Adult Anesthesia, Local / adverse effects* Cocaine / administration & dosage, adverse effects* Female Humans Male Middle Aged Myocardial Infarction / chemically induced* Myocardial Stunning / chemically induced* Nasal Septum / surgery* Phenylephrine / administration & dosage, adverse effects* Surgical Procedures, Elective |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine; 59-42-7/Phenylephrine |
| Comments/Corrections | |
Comment In:
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Arch Otolaryngol Head Neck Surg. 1996 Feb;122(2):207-8
[PMID:
8630221
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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