Document Detail

Cardiac cirrhosis: a rare manifestation of an uncorrected primum atrial septal defect.
MedLine Citation:
PMID:  19966572     Owner:  NLM     Status:  MEDLINE    
Atrial septal defects constitute the second most common cardiac congenital abnormality. These defects when undiagnosed during childhood, present in adulthood with symptoms of right heart failure. We describe a case of uncorrected ostium primum atrial septal defect that presented as liver failure in a 43-year-old woman. The patient was found to have liver cirrhosis and a complete work-up of hepatic causes for cirrhosis was negative. Further examination revealed an atrial primum septal defect. Liver cirrhosis in this patient was thought to be secondary to chronic congestion from the right heart failure resulting from the atrial septal defect. Although right heart failure is a known cause of cirrhosis, liver cirrhosis resulting specifically from an atrial septal defect is uncommon. In fact, an ostium primum atrial septal defect presenting as liver cirrhosis has not been well described. We present such a case to highlight this manifestation of atrial septal defect and also to reiterate that cardiac causes should always be considered in the differential diagnosis whenever a patient presents with liver cirrhosis.
Jayasree Pillarisetti; Jayant Nath; Loren Berenbom; Dhanunjaya Lakkireddy
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiovascular medicine (Hagerstown, Md.)     Volume:  11     ISSN:  1558-2035     ISO Abbreviation:  J Cardiovasc Med (Hagerstown)     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-07-30     Completed Date:  2010-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101259752     Medline TA:  J Cardiovasc Med (Hagerstown)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  689-91     Citation Subset:  IM    
University of Kansas Hospital, Kansas City, Kansas, USA.
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MeSH Terms
Cardiac Surgical Procedures
Diuretics / therapeutic use
Echocardiography, Transesophageal
Heart Failure / etiology*,  therapy,  ultrasonography
Heart Septal Defects, Atrial / complications*,  therapy,  ultrasonography
Liver Cirrhosis / etiology*,  pathology,  therapy
Treatment Outcome
Reg. No./Substance:

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