| Cardiac biplane strain imaging: initial in vivo experience. | |
| | |
MedLine Citation:
|
PMID: 20090186 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In this study, first we propose a biplane strain imaging method using a commercial ultrasound system, yielding estimation of the strain in three orthogonal directions. Secondly, an animal model of a child's heart was introduced that is suitable to simulate congenital heart disease and was used to test the method in vivo. The proposed approach can serve as a framework to monitor the development of cardiac hypertrophy and fibrosis. A 2D strain estimation technique using radio frequency (RF) ultrasound data was applied. Biplane image acquisition was performed at a relatively low frame rate (<100 Hz) using a commercial platform with an RF interface. For testing the method in vivo, biplane image sequences of the heart were recorded during the cardiac cycle in four dogs with an aortic stenosis. Initial results reveal the feasibility of measuring large radial, circumferential and longitudinal cumulative strain (up to 70%) at a frame rate of 100 Hz. Mean radial strain curves of a manually segmented region-of-interest in the infero-lateral wall show excellent correlation between the measured strain curves acquired in two perpendicular planes. Furthermore, the results show the feasibility and reproducibility of assessing radial, circumferential and longitudinal strains simultaneously. In this preliminary study, three beagles developed an elevated pressure gradient over the aortic valve (Deltap: 100-200 mmHg) and myocardial hypertrophy. One dog did not develop any sign of hypertrophy (Deltap = 20 mmHg). Initial strain (rate) results showed that the maximum strain (rate) decreased with increasing valvular stenosis (-50%), which is in accordance with previous studies. Histological findings corroborated these results and showed an increase in fibrotic tissue for the hearts with larger pressure gradients (100, 200 mmHg), as well as lower strain and strain rate values. |
| | |
Authors:
|
R G P Lopata; M M Nillesen; C N Verrijp; S K Singh; M M Y Lammens; J A W M van der Laak; H B van Wetten; J M Thijssen; L Kapusta; C L de Korte |
Related Documents
:
|
19359866 - Validation of strain gauges as a method of measuring precision of fit of implant bars. 19904346 - Raman spectroscopy of strained single-walled carbon nanotubes. 3559586 - The effect of total knee design on patellar strain. 18448876 - Strain reduction of the extensor carpi radialis brevis tendon proximal origin following... 9519596 - Transmission of vancomycin-resistant enterococcus among family members: a case study. 14497916 - The fecal flora of various strains of mice. its bearing on their susceptibility to endo... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-20 |
Journal Detail:
|
Title: Physics in medicine and biology Volume: 55 ISSN: 1361-6560 ISO Abbreviation: Phys Med Biol Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-02-03 Completed Date: 2010-04-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: England |
Other Details:
|
Languages: eng Pagination: 963-79 Citation Subset: IM |
Affiliation:
|
Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. R.Lopata@cukz.umcn.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Aortic Valve / ultrasonography Aortic Valve Stenosis / ultrasonography* Cardiomegaly / ultrasonography* Child Disease Models, Animal Dogs Echocardiography, Three-Dimensional / methods* Endomyocardial Fibrosis / ultrasonography Feasibility Studies Heart Defects, Congenital / ultrasonography Humans Pilot Projects Pressure Radio Waves Reproducibility of Results Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The relationship between the attenuation properties of breast microcalcifications and aluminum.
Next Document: Radio frequency noise from an MLC: a feasibility study of the use of an MLC for linac-MR systems.