Document Detail


Cardiac biomarkers and exercise duration and intensity during a cycle-touring event.
MedLine Citation:
PMID:  19638823     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the influence of age, training status, race time, and exercise intensity on the appearance of cardiac biomarkers after a cycle-touring event. DESIGN: Pre-post exercise measurements. SETTING: University of Zaragoza, Zaragoza, Spain. PARTICIPANTS: Ninety-one amateur cyclists. INTERVENTION: The 2005 Quebrantahuesos cycle-touring event (distance: 206 km; altitude difference: 3800 m). MAIN OUTCOME MEASURES: Cardiac troponin I (cTnI) and N-terminal pro-brain natriuretic peptide (NT-pro-BNP) were measured the day before and immediately after the race. Heart rate (HR) monitoring was performed on 55 cyclists during the race to evaluate exercise intensity. RESULTS: cTnI and NT-pro-BNP were significantly elevated immediately post race, with 43% of participants exhibiting cTnI levels greater than 0.04 microg/L and 65% of the participants measuring NT-pro-BNP levels greater than 125 ng/L. The cTnI increase was significantly associated with mean exercise intensity HR (r = 0.36, P < 0.01) but was not associated with age, training status, or race time. The increase in NT-pro-BNP correlated with race time (r = 0.40, P < 0.001) and training status (r = -0.36, P < 0.001) but was not associated with age or exercise intensity HR measures. CONCLUSIONS: These results suggest that, in part, exercise intensity (HR) is responsible for the cTnI increase and that race time is responsible for the increase in NT-pro-BNP. Future standardized endurance exercise trials are recommended to further elucidate the potentially differential effects of training status, exercise time, and intensity on post-exercise increases in cTnI and NT-pro-BNP.
Authors:
Enrique Serrano-Ostáriz; Alejandro Legaz-Arrese; José Luis Terreros-Blanco; Marta López-Ramón; Daniel Cremades-Arroyos; Luis Enrique Carranza-García; Silvia Izquierdo-Alvarez; Silvia Alvarez-Izquierdo; Pilar Bocos-Terraz; Pilar Boscos-Terraz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine     Volume:  19     ISSN:  1536-3724     ISO Abbreviation:  Clin J Sport Med     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-29     Completed Date:  2009-11-17     Revised Date:  2009-12-14    
Medline Journal Info:
Nlm Unique ID:  9103300     Medline TA:  Clin J Sport Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  293-9     Citation Subset:  IM    
Affiliation:
Section of Physical Education and Sports, University of Zaragoza, Zaragoza, Spain. enrise@unizar.es
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MeSH Terms
Descriptor/Qualifier:
Adult
Bicycling / physiology*
Biological Markers / blood
Heart Injuries / diagnosis,  physiopathology
Heart Rate
Humans
Middle Aged
Natriuretic Peptide, Brain / blood*
Peptide Fragments / blood*
Spain
Troponin I / blood*
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Peptide Fragments; 0/Troponin I; 0/pro-brain natriuretic peptide (1-76); 114471-18-0/Natriuretic Peptide, Brain
Comments/Corrections
Erratum In:
Clin J Sport Med. 2009 Sep;19(5):442
Note: Carranza-García, Luis Enrique [added]; Alvarez-Izquierdo, Silvia [corrected to Izquierdo-Alvarez, Silvia]; Boscos-Terraz, Pilar [corrected to Bocos-Terraz, Pilar]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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