Document Detail

Cardiac arrhythmias and rhabdomyolysis in Bartter-Gitelman patients.
MedLine Citation:
PMID:  20549246     Owner:  NLM     Status:  MEDLINE    
Recent data demonstrate that patients affected with hypokalemic salt-losing tubulopathies are prone to acute cardiac arrhythmias and rhabdomyolysis. The tendency to these potentially fatal complications is especially high if chronic hypokalemia is severe, in patients with diarrhea, vomiting or a prolonged QT interval on standard electrocardiography, in patients on drug management with compounds prolonging the electrocardiographic QT interval (including antiarrhythmic agents, some antihistamines, macrolides, antifungals, psychotropics, beta2-adrenergic agonists or cisapride), following acute alcohol abuse and during exercise. Cardiac arrhythmias and rhabdomyolysis occur with sufficient frequency in hypokalemic salt-losing tubulopathies to merit wider awareness of their presence and the preparation of specific prevention and management recommendations.
Cinzia Cortesi; Sebastiano A G Lava; Alberto Bettinelli; Fabiana Tammaro; Olivier Giannini; Maria Caiata-Zufferey; Mario G Bianchetti
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Publication Detail:
Type:  Editorial     Date:  2010-06-13
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  25     ISSN:  1432-198X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-08-19     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2005-8     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / etiology*
Bartter Syndrome / complications*
Rhabdomyolysis / etiology*

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