Document Detail

Cardiac arrhythmias in experimental subarachnoid hemorrhage.
MedLine Citation:
PMID:  898239     Owner:  NLM     Status:  MEDLINE    
Experimental subarachnoid hemorrhage (SAH) in dogs was produced by introducing blood into the subarachnoid space through a catheter connected to an artery of the animal. The intact animals and those with preserved vagi and heart sympathetic innervation, developed arrhythmias with short latencies which correlated with the sudden increase in the intracranial pressure. The animals with sections of both vagi and heart sympathetic innervation, but with an intact spinal cord, developed arrhythmias that were delayed and did not correlate with the changes in intracranial pressure. These arrhythmias were preceded by changes in the QT interval, T wave and ST segment. It was concluded that the arrhythmias could be produced either by direct autonomic discharges to the heart or by increased circulating and tissue catecholamines. The clinical implications of these findings are discussed.
B V Estanol; M V Loyo; J H Mateos; E Foyo; A Cornejo; J Guevara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  8     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:    1977 Jul-Aug
Date Detail:
Created Date:  1977-10-31     Completed Date:  1977-10-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  440-9     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / etiology*,  physiopathology
Blood Pressure
Disease Models, Animal
Heart / innervation*
Heart Rate
Intracranial Pressure
Subarachnoid Hemorrhage / complications*,  physiopathology
Sympathetic Nervous System / physiopathology*
Vagus Nerve / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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