Document Detail

Cardiac arrest upon induction of anesthesia in children with cardiomyopathy: an analysis of incidence and risk factors.
MedLine Citation:
PMID:  21736663     Owner:  NLM     Status:  Publisher    
Introduction:  It is thought that patients with cardiomyopathy have an increased risk of cardiac arrest on induction of anesthesia, but there is little available data. The purpose of this study was to identify the incidence and potential risk factors for cardiac arrest upon induction of anesthesia in children with cardiomyopathy in our institution. Methods:  A retrospective chart review was performed. Eligible patients included patients admitted between 1998 and 2008 with the International Statistical Classification of Disease code for cardiomyopathy (ICD-9 code 425) who underwent airway intervention for sedation or general anesthesia in the operating room, cardiac diagnostic and interventional unit (CDIU) or intensive care unit. Patients undergoing emergency airway intervention following cardiovascular collapse were excluded. For each patient, we recorded patient demographics, disease severity, anesthesia location, and anesthetic technique. Results:  One hundred and twenty-nine patients with cardiomyopathy underwent a total of 236 anesthetic events, and four cardiac arrests were identified. One was related to bradycardia (HR < 60), two were attributed to bradycardia in association with severe hypotension (systolic blood pressure < 45), and the fourth arrest was related to isolated severe hypotension. Two occurred in the operating suite and two in the CDIU. There was no resulting mortality. One patient progressed to heart transplantation. Multiple combinations of anesthetic drugs were used for induction of anesthesia. Conclusion:  We performed a review of the last 10 years of anesthesia events in children with cardiomyopathy. We report four cardiac arrests in two patients and 236 anesthetic events (1.7%). To the best of our knowledge, this is the largest review of these patients to date but is limited by its retrospective nature. The low cardiac arrest incidence prevents the identification of risk factors and the development of a cardiac arrest risk predictive clinical tool.
Johanne Lynch; Carolyne Pehora; Helen Holtby; Steven M Schwarz; Katherine Taylor
Related Documents :
18663283 - Nephrogenic systemic fibrosis.
3104273 - Combined imipenem/cilastatin and tobramycin therapy of multiresistant pseudomonas aerug...
21737283 - Susceptible gene single nucleotide polymorphism and hemorrhage risk in patients with br...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-8
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  -     ISSN:  1460-9592     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Blackwell Publishing Ltd.
 Our Lady's Children's Hospital, Crumlin, Dublin, Ireland  Department of Anesthesia, Toronto, Ontario, Canada  University of Toronto, Toronto, Ontario, Canada  Department of Critical Care Medicine, Toronto, Ontario, Canada  Labatt Family Heart Centre, Toronto, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  High Levels of Maternal Serum IL-17 and Activin A in Pregnant Women Affected by Systemic Lupus Eryth...
Next Document:  The Association of Betel Nut Chewing with Chronic Kidney Disease: A Retrospective 7-year Study in Ta...