Document Detail


Cardiac arrest secondary to indomethacin-induced renal failure: a case report.
MedLine Citation:
PMID:  2191029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute renal failure secondary to nonsteroidal anti-inflammatory agents is an uncommon occurrence, but may have serious or even lethal consequences. We present one such reaction resulting in cardiac arrest in a 59-year-old diabetic treated with indomethacin. Since presenting symptoms may be vague and unimpressive, one must consider this potential complication to make an early diagnosis and intervene appropriately. In addition when prescribing anti-inflammatory drugs such as indomethacin, one should be cautious in patients who are predisposed to the development of acute renal failure. Risk factors that should be considered are preexistent hepatorenal dysfunction, extracellular fluid volume contraction, and concomitant use of nephrotoxic drugs.
Authors:
M S Kharasch; K M Johnson; G R Strange
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of emergency medicine     Volume:  8     ISSN:  0736-4679     ISO Abbreviation:  J Emerg Med     Publication Date:    1990 Jan-Feb
Date Detail:
Created Date:  1990-07-17     Completed Date:  1990-07-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8412174     Medline TA:  J Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  IM    
Affiliation:
Northwestern University, Emergency Medicine Residency, Northwestern Memorial Hospital, Chicago, Illinois.
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MeSH Terms
Descriptor/Qualifier:
Cellulitis / complications*,  drug therapy
Coronary Disease / complications
Diabetes Mellitus, Type 1 / complications
Female
Heart Arrest / etiology*
Humans
Hyperkalemia / chemically induced,  complications*
Indomethacin / adverse effects*,  therapeutic use
Kidney Failure, Acute / chemically induced*,  complications
Middle Aged
Potassium Chloride / therapeutic use
Chemical
Reg. No./Substance:
53-86-1/Indomethacin; 7447-40-7/Potassium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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