Document Detail


Cardiac arrest induced by submucosal injection of epinephrine in a patient with variant angina.
MedLine Citation:
PMID:  20502771     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This case report describes a 35-year old male who experienced ventricular tachycardia induced by intramucosal injection of epinephrine (1:100,000). Under general anaesthesia with desflurane inhalation, 1.5% lidocaine containing 1:100,000 epinephrine was injected into the nasal mucosa for septoplasty. ST segment elevation and QRS widening occurred after 10 minutes and progressed to pulseless ventricular tachycardia. A sinus rhythm was restored after cardiopulmonary resuscitation with electrical cardioversion. The cardiac enzymes were significantly elevated after the event. Exercise-stress testing and coronary angiography were normal. However, an injection of acetylcholine into the coronary artery provoked vasospasm in the left anterior descending and circumflex arteries. This case illustrates an unusual response to low dose epinephrine with cardiac arrest induced in a patient with undiagnosed variant angina.
Authors:
Ji Young Lee; Sung Jin Hong; Jin Young Chon; So Young Kwon
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-06-01
Journal Detail:
Title:  Rhinology     Volume:  48     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-26     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  251-3     Citation Subset:  IM    
Affiliation:
Department of Anesthesiology and Pain Medicine, Catholic University of Korea College of Medicine, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Angina Pectoris, Variant / complications*,  diagnosis
Cardiopulmonary Resuscitation
Coronary Angiography
Electrocardiography
Epinephrine / administration & dosage,  adverse effects*
Exercise Test
Heart Arrest / chemically induced*
Humans
Male
Vasoconstrictor Agents / administration & dosage,  adverse effects*
Chemical
Reg. No./Substance:
0/Vasoconstrictor Agents; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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