Document Detail


Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine.
MedLine Citation:
PMID:  17263743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clonidine is a frequently administered alpha2-adrenergic agonist which can decrease heart rate and blood pressure. We present a case of a 5-year-old child with cerebral palsy and seizure disorder, receiving clonidine for restlessness, who presented for placement of a baclofen pump. Without the knowledge of the medical personnel, the patient's mother administered three doses of clonidine during the evening before and morning of surgery to reduce anxiety. During induction of anesthesia, the patient developed bradycardia and hypotension requiring cardiac resuscitation. There are no previous reports of clonidine-associated cardiac arrest in a child undergoing induction of anesthesia.
Authors:
Mark M Goldfinger; Paul A Tripi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  17     ISSN:  1155-5645     ISO Abbreviation:  Paediatr Anaesth     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-01-31     Completed Date:  2007-04-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  France    
Other Details:
Languages:  eng     Pagination:  270-2     Citation Subset:  IM    
Affiliation:
Division of Pediatric Anesthesiology, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio, USA. mark.goldfinger@uhhs.com
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MeSH Terms
Descriptor/Qualifier:
Adrenergic alpha-Agonists / administration & dosage,  adverse effects*
Anesthesia, General
Anesthetics, Inhalation
Cerebral Palsy / surgery*
Child, Preschool
Clonidine / administration & dosage,  adverse effects*
Female
Heart Arrest / chemically induced*,  therapy
Humans
Methyl Ethers
Preanesthetic Medication / adverse effects
Chemical
Reg. No./Substance:
0/Adrenergic alpha-Agonists; 0/Anesthetics, Inhalation; 0/Methyl Ethers; 28523-86-6/sevoflurane; 4205-90-7/Clonidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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