Document Detail

Cardiac arrest and blood ionized calcium levels.
MedLine Citation:
PMID:  3382105     Owner:  NLM     Status:  MEDLINE    
Blood ionized and total calcium levels, and pH values were obtained in 12 patients who were being ventilated and given external cardiac massage after having had an out-of-hospital cardiac arrest. On admission they had marked ionized hypocalcemia, with mean ionized calcium levels of 0.67 +/- 0.22 mmol/L, (range, 0.26 to 0.89), but normal total calcium levels. There was a positive correlation between pH and ionized calcium levels (r = 0.71). Of the six patients who were successfully resuscitated, four were discharged and two died; the other six could not be resuscitated and died. By comparison, ionized and total calcium levels obtained within 3 minutes of cardiac arrest were normal in 9 patients who had cardiac arrests in the intensive care unit or during surgery. All were discharged. These data are the first to document the occurrence of severe ionized hypocalcemia after out-of-hospital cardiac arrest. Hypocalcemia appears to be time-dependent and due essentially to extracellular complexing of calcium. Further work is needed to determine whether patients who have out-of-hospital cardiac arrests can benefit from calcium administration.
P Urban; D Scheidegger; B Buchmann; D Barth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of internal medicine     Volume:  109     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-07-28     Completed Date:  1988-07-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  110-3     Citation Subset:  AIM; IM    
Hôpital Cantonal Universitaire, Geneva, Switzerland.
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MeSH Terms
Aged, 80 and over
Calcium / blood*
Calcium Chloride / therapeutic use
Cations, Divalent / blood
Heart Arrest / blood*,  drug therapy
Hydrogen-Ion Concentration
Hypocalcemia / epidemiology
Middle Aged
Resuscitation / methods*
Reg. No./Substance:
0/Cations, Divalent; 10043-52-4/Calcium Chloride; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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