Document Detail


Cardiac arrest associated with sulprostone use during caesarean section.
MedLine Citation:
PMID:  9619226     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sulprostone, a synthetic prostaglandin with potent uterotonic action, has been shown to have a low complication rate in a large series. We present a case in which a bolus intravenous injection of sulprostone 30 micrograms was administered to treat postpartum haemorrhage during caesarean section. The 38-year-old patient with no previous cardiac or smoking history developed complete heart block, ventricular fibrillation and subsequent asystole. Cardiopulmonary resuscitation was successful after 45 minutes. Post resuscitation there was no myocardial infarction and she had complete neurological recovery. We postulate that the bolus of sulprostone resulted in possible coronary spasm that resulted in cardiac arrest.
Authors:
F G Chen; K F Koh; Y S Chong
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  26     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-08-31     Completed Date:  1998-08-31     Revised Date:  2006-08-28    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  298-301     Citation Subset:  IM    
Affiliation:
Department of Anaesthesia, National University of Singapore.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, General
Cesarean Section*
Dinoprostone / administration & dosage,  adverse effects,  analogs & derivatives*
Epinephrine / therapeutic use
Female
Heart Arrest / chemically induced*,  therapy
Heart Block / chemically induced*,  therapy
Humans
Injections, Intravenous
Postpartum Hemorrhage / drug therapy*
Pregnancy
Resuscitation
Sympathomimetics / therapeutic use
Ventricular Fibrillation / chemically induced*,  therapy
Chemical
Reg. No./Substance:
0/Sympathomimetics; 363-24-6/Dinoprostone; 51-43-4/Epinephrine; 60325-46-4/sulprostone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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