| Cardiac amyloidosis in a patient with multiple myeloma: a case report and review of literature. | |
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MedLine Citation:
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PMID: 19177424 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case of a 52-year-old man with multiple myeloma and rapidly progressive heart failure who died unexpectedly from a probable arrhythmia. Postmortem examination revealed infiltrative amyloid cardiomyopathy, a rare cause of predominantly diastolic myocardial disease. Cardiac amyloidosis should be considered in any patient presenting with congestive heart failure, preserved systolic function, and a discrepancy between a low QRS voltage on electrocardiography and an apparent left ventricular hypertrophy on sonogram. The pattern of left ventricular diastolic dysfunction changes during the course of amyloidosis and the classically described restrictive physiology occurs only in advanced stages of the disease. |
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Authors:
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David Sedaghat; Ramzan M Zakir; Jin Choe; Marc Klapholz; Muhamed Saric |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of clinical ultrasound : JCU Volume: 37 ISSN: 1097-0096 ISO Abbreviation: J Clin Ultrasound Publication Date: 2009 Mar-Apr |
Date Detail:
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Created Date: 2009-03-16 Completed Date: 2009-07-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401663 Medline TA: J Clin Ultrasound Country: United States |
Other Details:
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Languages: eng Pagination: 179-84 Citation Subset: IM |
Copyright Information:
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2009 Wiley Periodicals, Inc. |
Affiliation:
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Department of Medicine, New Jersey Medical School, 185 South Orange Avenue, I-538, Newark, NJ 07103, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amyloidosis
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complications*,
diagnosis,
genetics* Arrhythmias, Cardiac / complications Cardiomyopathy, Restrictive / complications*, diagnosis, genetics* Echocardiography Fatal Outcome Heart Failure / complications Heart Ventricles / ultrasonography Humans Hypertrophy, Left Ventricular / complications, ultrasonography Male Middle Aged Multiple Myeloma / complications*, drug therapy Ultrasonography, Doppler |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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