| Cardiac abnormalities in the fragile X syndrome. | |
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MedLine Citation:
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PMID: 2930667 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty three patients with fragile X syndrome underwent cardiovascular assessment. Echocardiography showed dilatation of the aortic root in 12 (52%) and mitral valve prolapse in five (22%), four of whom had an apical mid-systolic click on auscultation. Patients with fragile X syndrome have cardiac defects similar to those seen in other disorders of connective tissue such as Marfan's syndrome and Ehlers-Danlos syndrome. These, and other somatic features, suggest an underlying connective tissue dysplasia. |
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Authors:
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N Sreeram; C Wren; M Bhate; P Robertson; S Hunter |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British heart journal Volume: 61 ISSN: 0007-0769 ISO Abbreviation: Br Heart J Publication Date: 1989 Mar |
Date Detail:
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Created Date: 1989-05-23 Completed Date: 1989-05-23 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0370634 Medline TA: Br Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 289-91 Citation Subset: AIM; IM |
Affiliation:
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Department of Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Echocardiography Fragile X Syndrome / complications, pathology* Heart Defects, Congenital / complications, pathology* Humans Male Middle Aged Sex Chromosome Aberrations / pathology* |
| Comments/Corrections | |
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