Document Detail


Cardiac abnormalities in the acquired immunodeficiency syndrome. A prospective study with a clinical-pathological correlation in twenty-one adult patients.
MedLine Citation:
PMID:  10754583     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE - To evaluate the cardiac abnormalities and their evolution during the course of the acquired immunodeficiency syndrome, as well as to correlate clinical and pathological data. METHODS - Twenty-one patients, admitted to the hospital with the diagnosis of acquired immunodeficiency syndrome, were prospectively studied and followed until their death. Age ranged from 19 to 42 years (17 males). ECG and echocardiogram were also obtained every six months. After death, macro- and microscopic examinations were also performed. RESULTS - The most frequent causes of referral to the hospital were: diarrhea or repeated pneumonias, tuberculosis, toxoplasmosis or Kaposi sarcoma. The most frequent findings were acute or chronic pericarditis (42%) and dilated cardiomyopathy (19%). Four patients died of cardiac problems: infective endocarditis, pericarditis with pericardial effusion, bacterial myocarditis and infection by Toxoplasma gondii. CONCLUSION - Severe cardiac abnormalities were the cause of death in some patients. In the majority of the patients, a good correlation existed between clinical and anatomical-pathological data. Cardiac evaluation was important to detect early manifestations and treat them accordingly, even in asymptomatic patients.
Authors:
Herdy; Herdy; Almeida; Carvalho; Azevedo; Azevedo; Vasconcelos; Paiva; Tchou; Nascimento; Cosendey; Ferrari; Lopes
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Arquivos brasileiros de cardiologia     Volume:  73     ISSN:  1678-4170     ISO Abbreviation:  Arq. Bras. Cardiol.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2000-04-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421031     Medline TA:  Arq Bras Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  286-290     Citation Subset:  -    
Affiliation:
Universidade Federal Fluminense, Niterói, RJ, Brazil.
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