Document Detail


Cardiac MRI in pulmonary artery hypertension: correlations between morphological and functional parameters and invasive measurements.
MedLine Citation:
PMID:  20094890     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare cardiac MRI with right heart catheterisation in patients with pulmonary hypertension (PH) and to evaluate its ability to assess PH severity. MATERIALS AND METHODS: Forty patients were included. MRI included cine and phase-contrast sequences, study of ventricular function, cardiac cavity areas and ratios, position of the interventricular septum (IVS) in systole and diastole, and flow measurements. We defined four groups according to the severity of PH and three groups according to IVS position: A, normal position; B, abnormal in diastole; C, abnormal in diastole and systole. RESULTS: IVS position was correlated with pulmonary artery pressures and PVR (pulmonary vascular resistance). Median pulmonary artery pressures and resistance were significantly higher in patients with an abnormal septal position compared with those with a normal position. Correlations were good between the right ventricular ejection fraction and PVR, right ventricular end-systolic volume and PAP, percentage of right ventricular area change and PVR, and diastolic and systolic ventricular area ratio and PVR. These parameters were significantly associated with PH severity. CONCLUSION: Cardiac MRI can help to assess the severity of PH.
Authors:
Jean-Philippe Alunni; Bruno Degano; Catherine Arnaud; Laurent Tétu; Nathalie Blot-Soulétie; Alain Didier; Philippe Otal; Hervé Rousseau; Valérie Chabbert
Publication Detail:
Type:  Journal Article     Date:  2010-01-22
Journal Detail:
Title:  European radiology     Volume:  20     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-07     Completed Date:  2010-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1149-59     Citation Subset:  IM    
Affiliation:
Department of Radiology, CHU Rangueil, 1 avenue Jean-Poulhès, TSA 50032, 31059, Toulouse Cedex 9, France.
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MeSH Terms
Descriptor/Qualifier:
Area Under Curve
Blood Flow Velocity / physiology
Diastole
Female
Heart Catheterization
Heart Diseases / diagnosis*,  physiopathology*
Humans
Hypertension, Pulmonary / physiopathology*
Image Interpretation, Computer-Assisted / methods
Magnetic Resonance Imaging, Cine / methods*
Male
Middle Aged
Pulmonary Artery / physiopathology*
Severity of Illness Index
Statistics, Nonparametric
Systole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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