| Cardiac PET/CT for the Evaluation of Known or Suspected Coronary Artery Disease. | |
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MedLine Citation:
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PMID: 21918042 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Positron emission tomography (PET) is increasingly being applied in the evaluation of myocardial perfusion. Cardiac PET can be performed with an increasing variety of cyclotron- and generator-produced radiotracers. Compared with single photon emission computed tomography, PET offers lower radiation exposure, fewer artifacts, improved spatial resolution, and, most important, improved diagnostic performance. With its capacity to quantify rest-peak stress left ventricular systolic function as well as coronary flow reserve, PET is superior to other methods for the detection of multivessel coronary artery disease and, potentially, for risk stratification. Coronary artery calcium scoring may be included for further risk stratification in patients with normal perfusion imaging findings. Furthermore, PET allows quantification of absolute myocardial perfusion, which also carries substantial prognostic value. Hybrid PET-computed tomography scanners allow functional evaluation of myocardial perfusion combined with anatomic characterization of the epicardial coronary arteries, thereby offering great potential for both diagnosis and management. Additional studies to further validate the prognostic value and cost effectiveness of PET are warranted. © RSNA, 2011. |
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Authors:
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Marcelo F Di Carli; Venkatesh L Murthy |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiographics : a review publication of the Radiological Society of North America, Inc Volume: 31 ISSN: 1527-1323 ISO Abbreviation: Radiographics Publication Date: 2011 Sep-Oct |
Date Detail:
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Created Date: 2011-09-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8302501 Medline TA: Radiographics Country: United States |
Other Details:
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Languages: eng Pagination: 1239-54 Citation Subset: IM |
Affiliation:
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Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, and Noninvasive Cardiovascular Imaging Program, Departments of Radiology and Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, ASB-L1 037-C, Boston, MA 02115. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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