Document Detail

Carcinosarcoma of the orbit: report of two cases and review of the literature.
MedLine Citation:
PMID:  18562006     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To report the clinicopathologic features of 2 patients with carcinosarcoma of the orbit.
DESIGN: Case reports.
PARTICIPANTS: Two patients with orbital carcinosarcoma were identified.
METHODS: Retrospective chart review with clinicopathologic correlation and literature review.
MAIN OUTCOME MEASURES: Clinical examination, imaging studies, and histopathologic findings.
RESULTS: Two patients, a 56-year-old woman and a 91-year-old woman, with orbital carcinosarcoma were identified. Both tumors contained sarcomatous and carcinomatous components and invaded periorbital structures.
CONCLUSIONS: Carcinosarcoma may arise in the orbit or extend into the orbit from the paranasal sinuses. This malignant neoplasm should be aggressively treated with a combination of surgical resection, chemotherapy, and radiation therapy.
Sasapin G Prakalapakorn; C Robert Bernardino; Paul L Auclair; Hans E Grossniklaus
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2008-06-17
Journal Detail:
Title:  Ophthalmology     Volume:  115     ISSN:  1549-4713     ISO Abbreviation:  Ophthalmology     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-12-10     Completed Date:  2008-12-30     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2065-70     Citation Subset:  IM    
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
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MeSH Terms
Aged, 80 and over
Carcinosarcoma / pathology*,  radiography,  therapy
Combined Modality Therapy
Fatal Outcome
Middle Aged
Neoplasm Invasiveness
Orbital Neoplasms / pathology*,  radiography,  therapy
Retrospective Studies
Tomography, X-Ray Computed
Grant Support
P30 EY006360-25/EY/NEI NIH HHS; P30 EY06360/EY/NEI NIH HHS

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