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Carcinosarcoma of the Lung Associated with Neurofibromatosis Type 1: A Case Report.
MedLine Citation:
PMID:  22207441     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Neurofibromatosis or von Recklinghausen's disease is the most common inherited syndrome predisposing to neoplasia. Carcinosarcoma is a rare malignant mixed tumor of the lung. Association of carcinosarcoma of lung with Neurofibromatosis-1 is not common. A 57-year-old man presented with history of fever, cough, hemoptysis, breathlessness, weight loss, chest pain. Multiple cutaneous neurofibromas and cafè au lait spots were revealed by physical examination. A homogeneous opacity was found in the right middle and right upper zone on posterior-anterior chest radiography. A 8x8x7 cm mass that had irregular borders in right upper posterior and apical segment was seen on contrast enhanced chest computed tomography. On bronchoscopy, the lumen of right upper apical segment was obstructed with vegetating tumoral lesion. The biopsy taken from this region was diagnosed as carcinosarcoma by histopathological and immunohistochemical examination.A rare case with carcinosarcoma of the lung and Neurofibromatosis-1 was reported.
Authors:
Rana Cıtıl; Harun Ciralik; Ahmet Karsligıl; Pembe Oltulu; Derya Yenıbertız; Hamide Sayar; Esma Gürbüz
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Turk patoloji dergisi     Volume:  28     ISSN:  1018-5615     ISO Abbreviation:  -     Publication Date:  2012  
Date Detail:
Created Date:  2011-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440471     Medline TA:  Turk Patoloji Derg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  90-94     Citation Subset:  -    
Affiliation:
Department of Pathology, Kahramanmaraş State Hospital, KAHRAMANMARAŞ, TURKEY.
Vernacular Title:
Nörofibromatozis Tip 1 ile Akciğer Karsinosarkom Birlikteliği: Olgu Sunumu.
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