| Carcinoma ex pleomorphic adenoma of the parotid gland. | |
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MedLine Citation:
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PMID: 22287150 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BackgroundCarcinoma ex pleomorphic adenoma (CXPA) is a rare aggressive epithelial malignancy arising from a primary or recurrent benign mixed tumor. Only a few case reports describing the radiologic features of CXPA have been published.PurposeTo describe and characterize the magnetic resonance (MR) imaging findings of CXPA in the parotid gland and correlate them with pathologic findings.Material and MethodsThe MR images of surgically proven CXPA in the parotid gland of five men and five women ranging in age from 28 to 75 years (mean 52 years) were retrospectively reviewed. All MR images were evaluated with emphasis on the size, margin characteristics, extraparotid infiltration, the presence of an encapsulated component, and signal intensity on T2-weighted or short-inversion-time inversion recovery (STIR) images.ResultsThe average maximal diameter was 4.3 cm. All 10 tumors had ill-defined boundaries, and seven tumors showed extraparotid infiltration, reflecting invasive growth of the malignant component identified on histological examination. Eight tumors had a round encapsulated component and seven of those signal intensities were a mixture of hypo- and hyperintensity on T2-weighted or STIR images. Histological correlation of these components revealed fibrously encapsulated tumors containing hyalinization and myxoid tissue, suggesting degenerated pleomorphic adenoma. Invasive malignant components had non-specific and various signal intensities.ConclusionAn invasive parotid mass co-existing with a round encapsulated component is suggestive of carcinoma ex pleomorphic adenoma. |
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Authors:
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Nobuo Kashiwagi; Takamichi Murakami; Chikugo Takaaki; Yasuhiko Tomita; Kiyoshi Kawano; Katsuyuki Nakanishi; Kazunori Mori; Noriyuki Tomiyama |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-27 |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: - ISSN: 1600-0455 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, Kinki University School of Medicine, Osaka. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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