Document Detail

Carcinoma of the clitoris: a histologic study with cytokeratin profile.
MedLine Citation:
PMID:  8600082     Owner:  NLM     Status:  MEDLINE    
A carcinoma of the clitoris showed a variety of histologic features not usually encountered in squamous cell carcinoma of the vulva. In addition to poorly differentiated nonkeratinizing squamous cell carcinoma, there were large areas showing a transitional cell carcinoma pattern, as well as foci of spindle and anaplastic cells. The clitoral neoplasm also differed in its cytokeratin (CK) profile from that described in invasive squamous cell carcinoma of the vulva, especially with regard to the widespread staining for CK 18 and 19 in the former. Thus, our study suggests that some carcinomas of the clitoris differ from those of ordinary squamous cell carcinomas of the vulva. More cases should be studied using immunohistochemical methods in order to establish the full histopathologic and CK range of the former.
B Czernobilsky; A Gat; R Evron; R Dgani; H Ben-Hur; B Lifschitz-Mercer
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists     Volume:  14     ISSN:  0277-1691     ISO Abbreviation:  Int. J. Gynecol. Pathol.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1996-05-02     Completed Date:  1996-05-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8214845     Medline TA:  Int J Gynecol Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  274-8     Citation Subset:  IM    
Department of Pathology, Kaplan Hospital, Rehovot, Israel.
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MeSH Terms
Carcinoma, Transitional Cell / pathology*
Clitoris / pathology*
Keratins / analysis*
Vulvar Neoplasms / pathology*
Reg. No./Substance:
Erratum In:
Int J Gynecol Pathol 1995 Oct;14(4):366

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