Document Detail


Carcinoid tumours of the testis.
MedLine Citation:
PMID:  18190641     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To review previous reports of carcinoid (an endocrine tumour mostly of the gastrointestinal tract) tumours of the testis. METHODS: Carcinoid tumours of the testis are rare and can be divided into primary carcinoid (group 1), testicular metastasis from another location (group 2) and carcinoid within a testicular teratoma (group 3). A case of testicular carcinoid within our clinic prompted us to review previous reports; all the cases found were assessed for patient and tumour characteristics, diagnostic tools used, treatment and prognosis. RESULTS: In all, 62 cases were assessed and divided into groups 1 (44 patients), 2 (six) and 3 (12), respectively. Seven patients in group 1 developed metastases. A wide variety of diagnostic tools was used to search for other tumour sites. All patients were treated with orchidectomy. Three patients with a primary carcinoid were treated with adjuvant chemotherapy (two) or radiotherapy (one), with unknown results. All but one of the nine patients who died were known to have metastasis, either from a primary testicular carcinoid or testicular metastases from an intestinal carcinoid. CONCLUSION: When a testicular carcinoid tumour is discovered, other tumour sites should be excluded. The most useful diagnostic tools for this purpose seem to be urinary 5-hydroxyindoleacetic acid measurement, somatostatin receptor scintigraphy, computed tomography and video-capsule endoscopy. Localized testicular carcinoid tumours have an excellent prognosis after orchidectomy.
Authors:
Otto B Stroosma; Karl P J Delaere
Publication Detail:
Type:  Journal Article; Review     Date:  2008-01-08
Journal Detail:
Title:  BJU international     Volume:  101     ISSN:  1464-410X     ISO Abbreviation:  BJU Int.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-10     Completed Date:  2008-05-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886721     Medline TA:  BJU Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  1101-5     Citation Subset:  IM    
Affiliation:
Department of Urology, Atrium Medical Centre, Heerlen, The Netherlands. stroosma@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Carcinoid Tumor / diagnosis*,  secondary,  therapy
Chemotherapy, Adjuvant
Child
Humans
Hydroxyindoleacetic Acid / urine
Male
Middle Aged
Neoadjuvant Therapy
Orchiectomy / methods
Prognosis
Testicular Neoplasms / diagnosis*,  therapy
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
54-16-0/Hydroxyindoleacetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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