| Carcinoid syndrome from small bowel endocrine carcinoma in the absence of hepatic metastasis. | |
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MedLine Citation:
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PMID: 21903639 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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An 80-year-old male patient presented with abdominal pain, paroxysmal diaphoresis, diarrhoea and vomiting. CT scan revealed a small bowel endocrine carcinoma (or 'carcinoid' tumour), but the absence of hepatic disease. The lesion was excised 'en-bloc'. Intra-operatively, there was wide fluctuation in blood pressure associated with tumour manipulation, with hyper- and hypotension. Carcinoid syndrome usually occurs from gastrointestinal tumours when hepatic metastases occur, causing flushing, diarrhoea, bronchoconstriction and murmurs from cardiac valvular lesions. This patient did not have radiological evidence of hepatic metastasis, but the syndrome could still occur with midgut tumours via local invasion of the retroperitoneal circulation, or by action of substances other than serotonin that do not undergo hepatic metabolism. |
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Authors:
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Sayan Datta; Nigel Williams; Sari Suortamo; Asif Mahmood; Colin Oliver; Nicholas Hedley; Pijush Ray |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-7 |
Journal Detail:
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Title: Age and ageing Volume: - ISSN: 1468-2834 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375655 Medline TA: Age Ageing Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry CV2 2DX, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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