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Carcinogenicity of food mutagens.
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MedLine Citation:
PMID:  8781358     Owner:  NLM     Status:  MEDLINE    
Cancer cells are produced by the accumulation of genetic alterations in somatic cells. Those genetic alterations are produced by xenobiotics, which enter the human body from the environment, and by autobiotics, which are produced in the human body. Food contains many different types of xenobiotic mutagens/carcinogens and tumor promoters. Food can influence the formation of autobiotic mutagens/carcinogens and give rise to tumor-promoting conditions. In spite of this, it can also contain many antimutagenic, anticarcinogenic, and antitumor-promoting substances. Carcinogenic risk and anticarcinogenic efficacy are hard to express quantitatively; however, holistic approaches that are designed to improve lifestyle are realistic for cancer prevention.
T Sugimura; M Nagao; K Wakabayashi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Environmental health perspectives     Volume:  104 Suppl 3     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1996 May 
Date Detail:
Created Date:  1997-03-19     Completed Date:  1997-03-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  429-33     Citation Subset:  IM    
National Cancer Center, Tokyo, Japan.
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MeSH Terms
Amines / adverse effects
Antimutagenic Agents / pharmacology
Carcinogens, Environmental / adverse effects*
Food / adverse effects*
Food Contamination
Heterocyclic Compounds / adverse effects
Mutagens / adverse effects*
Neoplasms / chemically induced*,  genetics,  prevention & control
Reg. No./Substance:
0/Amines; 0/Antimutagenic Agents; 0/Carcinogens, Environmental; 0/Heterocyclic Compounds; 0/Mutagens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
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Print publication date: Month: 5 Year: 1996
Volume: 104 Issue: Suppl 3
First Page: 429 Last Page: 433
ID: 1469643
PubMed Id: 8781358

Carcinogenicity of food mutagens.
T Sugimura
M Nagao
K Wakabayashi
National Cancer Center, Tokyo, Japan.

Article Categories:
  • Research Article

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