Document Detail

Carcinoembryonic antigen test for recurrent colorectal carcinoma. Inadequacy for early detection.
MedLine Citation:
PMID:  628054     Owner:  NLM     Status:  MEDLINE    
Serum carcinoembryonic antigen (CEA) tests were performed on 36 patients with histologically proved locally recurrent or residual malignant disease after resection of colorectal carcinoma but with no clinical evidence of distant metastasis. Only nine patients (25%) had abnormal CEA levels of greater than 5 ng/ml despite the fact that most patients had had symptoms of recurrence for several months. Among the nine of our patients, none had CEA values greater than 5 ng/ml, and only three had levels greater than 2.5 ng/ml (3.4, 3.8, and 4.7 ng/ml). The CEA assay is not a sensitive test for early detection of recurrence of colorectal carcinoma.
C G Moertel; A J Schutt; V L Go
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  JAMA     Volume:  239     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-04-26     Completed Date:  1978-04-26     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1065-6     Citation Subset:  AIM; IM    
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MeSH Terms
Adenocarcinoma / diagnosis
Carcinoembryonic Antigen / analysis*
Colonic Neoplasms / diagnosis*
Evaluation Studies as Topic
Rectal Neoplasms / diagnosis*
Time Factors
Reg. No./Substance:
0/Carcinoembryonic Antigen

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