Document Detail


Carbon nanotubes in neural interfacing applications.
MedLine Citation:
PMID:  21245526     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Carbon nanotubes (CNT) are remarkable materials with a simple and inert molecular structure that gives rise to a range of potentially valuable physical and electronic properties, including high aspect ratio, high mechanical strength and excellent electrical conductivity. This review summarizes recent research on the application of CNT-based materials to study and control cells of the nervous system. It includes the use of CNT as cell culture substrates, to create patterned surfaces and to study cell-matrix interactions. It also summarizes recent investigations of CNT toxicity, particularly as related to neural cells. The application of CNT-based materials to directing the differentiation of progenitor and stem cells toward neural lineages is also discussed. The emphasis is on how CNT surface chemistry and nanotopography can be altered, and how such changes can affect neural cell function. This knowledge can be applied to creating improved neural interfaces and devices, as well as providing new approaches to neural tissue engineering and regeneration.
Authors:
Christopher M Voge; Jan P Stegemann
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-19
Journal Detail:
Title:  Journal of neural engineering     Volume:  8     ISSN:  1741-2552     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101217933     Medline TA:  J Neural Eng     Country:  -    
Other Details:
Languages:  ENG     Pagination:  011001     Citation Subset:  -    
Affiliation:
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
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