Document Detail

Carbon nanotubes in macrophages: imaging and chemical analysis by X-ray fluorescence microscopy.
MedLine Citation:
PMID:  18672943     Owner:  NLM     Status:  PubMed-not-MEDLINE    
X-ray fluorescence microscopy (microXRF) is applied for the first time to study macrophages exposed to unpurified and purified single-walled (SW) and multiwalled (MW) carbon nanotubes (CNT). Investigating chemical elemental distributions allows one to (i) image nanotube localization within a cell and (ii) detect chemical modification of the cell after CNT internalization. An excess of calcium is detected for cells exposed to unpurified SWCNT and MWCNT and related toxicological assays are discussed.
Cyrill Bussy; Julien Cambedouzou; Sophie Lanone; Emilie Leccia; Vasile Heresanu; Mathieu Pinault; Martine Mayne-L'hermite; Nathalie Brun; Claudie Mory; Marine Cotte; Jean Doucet; Jorge Boczkowski; Pascale Launois
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Publication Detail:
Type:  Journal Article     Date:  2008-08-02
Journal Detail:
Title:  Nano letters     Volume:  8     ISSN:  1530-6984     ISO Abbreviation:  Nano Lett.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-12     Completed Date:  2008-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101088070     Medline TA:  Nano Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2659-63     Citation Subset:  -    
Laboratoire de Physique des Solides, UMR 8502 CNRS, Universite Paris Sud, Bat. 510, Orsay F-91405, France.
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