| Carbon monoxide assessment of smoking in chronic obstructive pulmonary disease. | |
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MedLine Citation:
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PMID: 2589127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chronic Obstructive Pulmonary Disease (COPD) is a major, often fatal, drain on health-care resources. Most cases of COPD result from Tobacco Dependence, and smoking cessation slows COPD's progression. But there is very little information on treating Tobacco Dependence in COPD patients. In preparation for clinical trials using monetary payments to motivate reduced smoking, as assessed by breath carbon monoxide (CO) levels in COPD patients, we have addressed three issues. First, surveying 182 advanced COPD patients, we found that CO levels above 8 parts per million (ppm) were strongly associated with a self-report of current smoking, and that CO levels correlated neither with COPD severity, nor with age: about one-third of these patients were currently smoking. Second, among 12 still-smoking COPD patients serially observed for 8 h. CO half-life averaged about 6.5 h. Third, 8 patients reinforced with lottery tickets for CO reductions significantly reduced CO levels during 2 test weeks, mainly by deferring smoking before scheduled CO measurements. |
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Authors:
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T J Crowley; A E Andrews; J Cheney; G Zerbe; T L Petty |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Addictive behaviors Volume: 14 ISSN: 0306-4603 ISO Abbreviation: Addict Behav Publication Date: 1989 |
Date Detail:
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Created Date: 1989-12-22 Completed Date: 1989-12-22 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7603486 Medline TA: Addict Behav Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 493-502 Citation Subset: IM |
Affiliation:
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Addiction Research and Treatment Service, University of Colorado School of Medicine, Denver 80262. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Air Pollution
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adverse effects Breath Tests* Carbon Monoxide / pharmacokinetics* Female Follow-Up Studies Forced Expiratory Volume Humans Lung Diseases, Obstructive / blood*, therapy Male Middle Aged Oxygen Inhalation Therapy Smoking / blood*, therapy |
| Grant Support | |
ID/Acronym/Agency:
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DA 03961/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
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630-08-0/Carbon Monoxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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