| Carbon-laden macrophages in pleural fluid of crack smokers. | |
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MedLine Citation:
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PMID: 8599915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Carbon-laden macrophages in bronchoalveolar lavage have been noted to be associated with a history of crack smoking. We report herein the finding of carbon-laden macrophages in four cytological preparations of pleural fluid from two crack smokers. The etiology of the two patients' pleural effusions differed; neither had a bronchopleural fistula. Patient 1 had AIDS, Pneumocystis carinii pneumonia, and Kaposi's sarcoma of the right lung with an associated bilateral pleural effusion. Patient 2 was HIV seropositive, had pulmonary tuberculosis, hepatitis A, B, and C, cardiomyopathy, pulmonary embolism, and bilateral pleural effusions, the latter of which were probably due to cardio-pulmonary dysfunction. An additional two crack smokers with pleural effusions due to malignancy, one primary pulmonary adenocarcinoma and the other metastatic melanoma, did not have carbon-like material in their pleural fluid cytology. We hypothesize that intracellular accumulation of carbonaceous material in the lung parenchyma and pleural space occurs when normal clearance mechanisms are overwhelmed. |
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Authors:
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B Singh; E Greenebaum; R Cole |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Diagnostic cytopathology Volume: 13 ISSN: 8755-1039 ISO Abbreviation: Diagn. Cytopathol. Publication Date: 1995 Nov |
Date Detail:
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Created Date: 1996-04-26 Completed Date: 1996-04-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8506895 Medline TA: Diagn Cytopathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 316-9 Citation Subset: IM; X |
Affiliation:
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Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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complications Adult Carbon / analysis* Cardiomyopathies / complications Crack Cocaine / administration & dosage, adverse effects* HIV Seropositivity / complications Hepatitis A / complications Hepatitis B / complications Hepatitis C / complications Humans Lung Neoplasms / complications Macrophages / chemistry* Male Middle Aged Pleural Effusion / etiology, pathology* Pneumonia, Pneumocystis / complications Sarcoma, Kaposi / complications Smoking Tuberculosis / complications |
| Chemical | |
Reg. No./Substance:
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0/Crack Cocaine; 7440-44-0/Carbon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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