Document Detail


Carbon dioxide wedged arterial splenoportography: a new technique--a case report and an experimental study.
MedLine Citation:
PMID:  19235576     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Patients with splenic vein occlusion may present a diagnostic problem when the location, morphology, and cause of the obstructive lesion and the associated collateral veins cannot be clearly defined by standard diagnostic imaging modalities such as computed tomography, magnetic resonance venography, or indirect splenoportography (arterial portography). PURPOSE: To evaluate the safety and effectiveness of carbon dioxide (CO(2)) wedged arterial splenoportography for definitive investigation of splenic vein occlusion. MATERIAL AND METHODS: Following unsuccessful diagnosis with computed tomography and standard contrast arterial portography in a patient with recurrent gastric variceal bleeding, CO(2) was injected into a wedged splenic arterial catheter and successfully outlined splenic vein occlusion and gastric varices. Our experience with this patient prompted us to perform an experimental study in swine to evaluate the safety and effectiveness of CO(2) wedged arterial splenoportography for visualization of the splenic and portal veins. A microcatheter was advanced coaxially and wedged into the splenic arteries of three pigs. After checking the wedged positioning with contrast medium injection, CO(2) was injected manually and the splenic region imaged. The spleens were then removed for gross and microscopic examinations. RESULTS: In the patient, CO(2) wedged arterial splenoportography demonstrated gastric varices associated with splenic vein occlusion. In all animals, CO(2) wedged arterial splenoportography visualized the splenic and portal veins. No CO(2) extravasations occurred in the spleen. Gross and microscopic examinations revealed no evidence of splenic rupture or intrasplenic hematoma. CONCLUSION: CO(2) wedged arterial splenoportography may be a useful method for visualizing gastric varices associated with splenic vein occlusion. This new technique has the potential to replace the standard splenic arterial portography for visualization of splenic and portal veins, thus eliminating the need for injection of a large volume of iodinated contrast material. Further clinical studies are justified to evaluate this technique.
Authors:
S C H Yu; K J Cho
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta radiologica (Stockholm, Sweden : 1987)     Volume:  50     ISSN:  1600-0455     ISO Abbreviation:  Acta Radiol     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-17     Completed Date:  2009-04-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706123     Medline TA:  Acta Radiol     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  265-9     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China. simonyu@cuhk.edu.hk
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MeSH Terms
Descriptor/Qualifier:
Angiography, Digital Subtraction / methods*
Animals
Carbon Dioxide / diagnostic use*
Collateral Circulation / physiology
Constriction, Pathologic / complications,  radiography
Contrast Media*
Embolization, Therapeutic
Esophageal and Gastric Varices / etiology,  radiography*,  therapy
Gastrointestinal Hemorrhage / etiology,  radiography*,  therapy
Humans
Liver Neoplasms / radiography,  secondary
Male
Middle Aged
Neuroendocrine Tumors / radiography,  secondary
Pancreatic Neoplasms / radiography
Portography / methods*
Splenic Vein / radiography*
Swine
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Contrast Media; 124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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