Document Detail


Carbon-Carbon Bond-Forming Enzymes for the Synthesis of Non-natural Amino Acids.
MedLine Citation:
PMID:  21956557     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
An enzymatic methodology for the preparation of β-hydroxy-α-amino acid derivatives is described. The method consists of the stereoselective aldol addition reaction of glycine to N-Cbz-amino aldehydes furnishing 3-hydroxy-2,4-diaminobutyric derivatives.
Authors:
Pere Clapés; Jesús Joglar; Mariana Gutiérrez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  794     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2012  
Date Detail:
Created Date:  2011-09-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  73-85     Citation Subset:  IM    
Affiliation:
Department of Chemical Biology and Molecular Modeling, Instituto de Química Avanzada de Cataluña IQAC-CSIC, Barcelona, Spain, pere.clapes@iqac.csic.es.
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