Document Detail


Carbon-13 nuclear magnetic resonance spectroscopic study of teichuronic acid from Micrococcus luteus cell walls. Comparison of the polysaccharide isolated from cells with that synthesized in vitro.
MedLine Citation:
PMID:  7295649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Teichuronic acid isolated from the cell walls of Micrococcus luteus has been examined by natural-abundance (13)C NMR spectroscopy. Proton-decoupled and proton-coupled spectra were obtained for native teichuronic acid and also after the teichuronic acid had been oxidized with periodate and reduced with borohydride. The spectra are consistent with the structure [ManNAcUAp-( beta -1,6)-G1cp-( alpha -1,4)]n. Teichuronic acid synthesized in vitro from suitable substrates by the particulate enzyme fraction obtained from M. luteus yielded a (13)C NMR spectrum which is indistinguishable from that of the native teichuronic acid, indicating a structural identity of the teichuronic acid synthesized in vitro with that isolated from cell walls.
Authors:
S D Johnson; K P Lacher; J S Anderson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biochemistry     Volume:  20     ISSN:  0006-2960     ISO Abbreviation:  Biochemistry     Publication Date:  1981 Aug 
Date Detail:
Created Date:  1982-01-09     Completed Date:  1982-01-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370623     Medline TA:  Biochemistry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  4781-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Wall / metabolism*
Magnetic Resonance Spectroscopy
Micrococcus / metabolism*
Polysaccharides, Bacterial / analysis*,  biosynthesis
Uronic Acids / analysis*,  biosynthesis
Grant Support
ID/Acronym/Agency:
AI-08295/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Polysaccharides, Bacterial; 0/Uronic Acids; 37251-79-9/teichuronic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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