Document Detail

Carbohydrate nutrition, glycemic index, and the 10-y incidence of cataract.
MedLine Citation:
PMID:  17991665     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although dietary carbohydrates are thought to play a role in cataractogenesis, few epidemiologic studies have examined links between carbohydrate nutrition and cataract. OBJECTIVES: We investigated the associations between dietary glycemic index (GI), glycemic load (GL), total carbohydrate intake, and 10-y incident nuclear, cortical, and posterior subcapsular cataract. DESIGN: Of 3654 baseline participants in an Australian population aged >/=49 y (1992-1994), 933 were seen after 5 and/or 10 y, had completed a detailed semiquantitative food-frequency questionnaire, had no previous cataract surgery or baseline cataract, and had photographs taken to assess incident cataract with the Wisconsin Cataract Grading System. Dietary information was collected with a validated food questionnaire. GI was calculated from a customized database of Australian foods. GI, GL, and all other nutrients were energy adjusted. Hazard ratios (HRs) and 95% CIs were calculated with the use of discrete logistic models. RESULTS: After age, sex, diabetes, and other factors were controlled for, each SD increase in GI significantly predicted incident cortical cataract (HR: 1.19; 95% CI: 1.01, 1.39). Participants within the highest compared with the lowest quartile of GI were more likely to develop incident cortical cataract (HR: 1.77; 95% CI: 1.13, 2.78; P for trend = 0.035). These findings were similar after excluding participants with diabetes, although they were slightly attenuated and marginally nonsignificant (HR: 1.16; 95% CI: 0.98, 1.37, per SD increase in GI). No association was found between GI and nuclear or posterior subcapsular cataract and between GL or carbohydrate quantity and any cataract subtype. CONCLUSION: In an Australian cohort, poorer dietary carbohydrate quality, reflected by high GI, predicted incident cortical cataract.
Jennifer Tan; Jie Jin Wang; Victoria Flood; Shweta Kaushik; Alan Barclay; Jennie Brand-Miller; Paul Mitchell
Related Documents :
25451585 - The evolving content of meals in great britain. results of a survey in 2012 in comparis...
10644555 - Nutrient tasting and signaling mechanisms in the gut. iv. there is more to taste than m...
23755895 - Current trends in detecting non-o157 shiga toxin-producing escherichia coli in food.
20100375 - Glycaemic index of indian flatbreads (rotis) prepared using whole wheat flour and 'atta...
21599955 - Association between proximity to and coverage of traditional fast-food restaurants and ...
12436425 - Nicotinic receptor-mediated effects on appetite and food intake.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  86     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-09     Completed Date:  2007-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1502-8     Citation Subset:  AIM; IM    
Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Westmead Hospital, Sydney, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Australia / epidemiology
Cataract / epidemiology*
Dietary Carbohydrates / administration & dosage*
Glycemic Index*
Middle Aged
Time Factors
Reg. No./Substance:
0/Dietary Carbohydrates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Dietary glycemic load, added sugars, and carbohydrates as risk factors for pancreatic cancer: the Mu...
Next Document:  Substantial intergenerational increases in body mass index are not explained by the fetal overnutrit...