Document Detail


Carbaryl effects on growth and development in suspension cultures of wild carrot.
MedLine Citation:
PMID:  823987     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Carbaryl has been demonstrated to inhibit growth of carrot suspension cultures at 10 and 20 ppm. The specific activities of RNA and protein increased at 20 ppm. Total RNA was relatively unchanged at any concentration while total protein was reduced considerably at 20 ppm. Embryo development was inhibited by increasing concentrations of carbaryl. Thin layer chromatography indicated considerable degradation of carbaryl to 1-naphthol. When 1-naphthol was tested in this system it was shown to elicit the same inhibitory effects on growth as carbaryl, suggesting that the 1-naphthol residue is itself a potent inhibitor of tissue growth and development.
Authors:
Z S Wochok; T Welch
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Bulletin of environmental contamination and toxicology     Volume:  16     ISSN:  0007-4861     ISO Abbreviation:  Bull Environ Contam Toxicol     Publication Date:  1976 Sep 
Date Detail:
Created Date:  1976-12-30     Completed Date:  1976-12-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0046021     Medline TA:  Bull Environ Contam Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  325-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Carbaryl / metabolism,  pharmacology*
Cells, Cultured
Growth / drug effects
Naphthols / pharmacology
Plant Proteins / metabolism
Plants / growth & development,  metabolism
RNA / biosynthesis
Chemical
Reg. No./Substance:
0/Naphthols; 0/Plant Proteins; 63-25-2/Carbaryl; 63231-63-0/RNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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