Document Detail


Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications.
MedLine Citation:
PMID:  17400276     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pKa's of the 6-CH groups of 1,3-dimethyluracil, N-methyl-2-pyridone, and N-methyl-4-pyridone were determined through their reactions with bases derived from carbon acids with known pKa and the reactions of their corresponding carbanions with the carbon acids. No correlation between the stability of the carbanions and the rate of decarboxylation of corresponding carboxylic acids was found.
Authors:
Fong Ying Yeoh; Roxanne R Cuasito; Christina C Capule; Freeman M Wong; Weiming Wu
Related Documents :
24631256 - Antihypertensive effect of caffeic acid and its analogs through dual renin-angiotensin-...
12559586 - Influence of the morphology of poly(egdma-co-hema) on the chemical modifications and re...
18215026 - Direct observation of nh2* reactions with oxygen, amino acids, and melanins.
22125156 - Wheat gluten amino acid analysis by high-performance anion-exchange chromatography with...
18643866 - Enhancing the quality of aged latent fingerprints developed by superglue fuming: loss a...
2912746 - The convulsant effects of kainic acid microinjections into cerebral cortex are concentr...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2007-04-02
Journal Detail:
Title:  Bioorganic chemistry     Volume:  35     ISSN:  0045-2068     ISO Abbreviation:  Bioorg. Chem.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-03     Completed Date:  2007-09-05     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  1303703     Medline TA:  Bioorg Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  338-43     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anions / chemistry*
Carboxylic Acids / chemistry
Decarboxylation
Orotic Acid / analogs & derivatives*,  chemistry
Pyridones / chemistry
Grant Support
ID/Acronym/Agency:
5 S06 GM52588/GM/NIGMS NIH HHS; S06 GM052588/GM/NIGMS NIH HHS; S06 GM052588-140008/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Anions; 0/Carboxylic Acids; 0/Pyridones; 61H4T033E5/Orotic Acid
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Removal and fate of Cryptosporidium parvum, Clostridium perfringens and small-sized centric diatoms ...
Next Document:  Spectroscopic investigation of magnetite surface for the reduction of hexavalent chromium.