| Carbamylated hemoglobin in prerenal azotemia. | |
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MedLine Citation:
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PMID: 8569946 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Carbamylated hemoglobin (Carb Hb) levels were measured in 16 patients with a documented transient rise in BUN due to prerenal azotemia, in whom BUN levels before and after the episode were normal. They were compared with 13 controls. Carb Hb was expressed as carbamyl valine concentrations, which were significantly higher in the patients (166 micrograms/g Hb) than in controls (95.3 micrograms/g Hb, p < 0.01). The mean maximum BUN level in the patients was 51.8 +/- 23.9 mg/dl. There was a significant correlation between the product of mean BUN level times the number of days of BUN elevation, and the Carb Hb level (r = 0.5197; p < 0.05). There was no correlation between Carb Hb and either mean BUN level or maximum BUN level. Elevated Carb Hb was seen after a minimum of 4 days' BUN elevation. Four patients had no elevation of Carb Hb despite elevated BUN levels. Conclusion: Carb Hb may be elevated after a minimum of 4 days' transient BUN elevation; Carb Hb is not useful in differentiating between mild acute renal failure and prerenal azotemia. |
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Authors:
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J M Frazao; R H Barth; G M Berlyne |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nephron Volume: 71 ISSN: 0028-2766 ISO Abbreviation: Nephron Publication Date: 1995 |
Date Detail:
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Created Date: 1996-03-05 Completed Date: 1996-03-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0331777 Medline TA: Nephron Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 153-5 Citation Subset: IM |
Affiliation:
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Department of Nephrology, Department of Veterans Affairs Medical Center, Brooklyn, NY 11209, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Blood Urea Nitrogen Carbamates / blood* Creatinine / blood Diagnosis, Differential Female Hemoglobins / metabolism* Humans Kidney Diseases / blood* Kidney Failure / diagnosis Male Middle Aged Time Factors Uremia / blood*, diagnosis Valine / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Carbamates; 0/Hemoglobins; 60-27-5/Creatinine; 7004-03-7/Valine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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