Document Detail

Carbamazepine-induced systemic lupus erythematosus-like disease.
MedLine Citation:
PMID:  1295628     Owner:  NLM     Status:  MEDLINE    
A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy. Clinical symptoms and leukopenia normalized after discontinuation of CBZ and administration of prednisolone at 40 mg. The cases of CBZ-induced SLE reported in the literature were reviewed.
T Kanno; M Miyata; Y Kazuta; Y Sato; T Nishimaki; R Kasukawa
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  31     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1993-04-22     Completed Date:  1993-04-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1303-5     Citation Subset:  IM    
Department of Internal Medicine II, Fukushima Medical College, Japan.
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MeSH Terms
Carbamazepine / adverse effects*
Epilepsy / drug therapy
Lupus Erythematosus, Systemic / chemically induced*,  diagnosis,  drug therapy
Prednisolone / therapeutic use
Reg. No./Substance:
298-46-4/Carbamazepine; 50-24-8/Prednisolone

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