Document Detail

Capture-recapture analysis of ascertainment by active surveillance in the British Congenital Cataract Study.
MedLine Citation:
PMID:  9888448     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Active surveillance has not been widely used in ophthalmologic research. The use of capture-recapture analysis to determine completeness of case ascertainment by active surveillance in a national study of congenital cataract is reported. METHODS: In 1 year in the United Kingdom, all incident diagnoses of congenital and infantile cataract were notified through independent ophthalmic and pediatric active surveillance schemes. Two-source capture-recapture analysis was applied to assess the level of ascertainment of infants (age < or = 12 months) by these two schemes. RESULTS: In a 12-month period, 161 infants with newly diagnosed congenital or infantile cataract were notified. Overall ascertainment was estimated to be 92% complete and was higher in the ophthalmic (85%) than in the pediatric (45%) scheme. Comparison with the number of cases expected, from disease frequency reported in existing national congenital anomaly notification systems, suggests previous underascertainment of congenital cataract in such passive reporting systems. CONCLUSIONS: This study shows the effectiveness of two-source active surveillance in identifying a nationally representative cohort that will provide better information about this disorder than has been available from sources of routinely collected data.
J S Rahi; C Dezateux
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  40     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-01-20     Completed Date:  1999-01-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  236-9     Citation Subset:  IM    
Department of Epidemiology and Public Health, Institute of Child Health/Great Ormond Street Hospital, London, United Kingdom.
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MeSH Terms
Cataract / congenital*,  epidemiology*
Disease Notification
Epidemiologic Methods*
Great Britain / epidemiology
Infant, Newborn
Population Surveillance*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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