Document Detail

Capsule endoscopy in diagnosis of small bowel Crohn's disease.
MedLine Citation:
PMID:  15112357     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate the effectiveness of wireless capsule endoscopy in patients with suspected Crohn's disease (CD) of the small bowel undetected by conventional modalities, and to determine the diagnostic yield of M2A Given Capsule. METHODS: From May 2002 to April 2003, we prospectively examined 20 patients with suspected CD by capsule endoscopy. The patients had the following features: abdominal pain, weight loss, positive fecal occult blood test, iron deficiency anaemia, diarrhoea and fever. All the patients had normal results in small bowel series (SBS) and in upper and lower gastrointestinal endoscopy before they were examined. Mean duration of symptoms before diagnosis was 6.5 years. RESULTS: Of the 20 patients, 13 (65%) were diagnosed as CD of the small bowel according to the findings of M2A Given Capsule. The findings detected by the capsule were mucosal erosions (2 patients), aphthas (5 patients), nodularity (1 patient), large ulcers (2 patients), and ulcerated stenosis (3 patients). The distribution of the lesions was mainly in the distal part of the small bowel, and the mild degree of lesions was 54%. CONCLUSION: Wireless capsule endoscopy is effective in diagnosing patients with suspected CD undetected by conventional diagnostic methods. It can be used to detect early lesions in the small bowel of patients with CD.
Zhi-Zheng Ge; Yun-Biao Hu; Shu-Dong Xiao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  10     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-04-27     Completed Date:  2004-10-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  1349-52     Citation Subset:  IM    
Department of Gastroenterology, Renji Hospital, Shanghai Institute of Digestive Disease, Shanghai Second Medical University, Shanghai 200001, China.
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MeSH Terms
Crohn Disease / diagnosis*,  drug therapy,  pathology
Endoscopy, Gastrointestinal / methods*
Intestine, Small / pathology*
Middle Aged
Prospective Studies
Steroids / therapeutic use
Telemetry / instrumentation,  methods*
Video Recording
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