Document Detail

Capsule endoscopy changes patient management in routine clinical practice.
MedLine Citation:
PMID:  17357836     Owner:  NLM     Status:  MEDLINE    
Our objective was to evaluate the diagnostic yield and effect of capsule endoscopy on patient management in routine clinical practice. Three hundred examinations were performed (176 females; mean age, 51 years), with a median follow-up of 17 months. Indications included overt bleeding (n=55), anemia (n=104), suspected Crohn's disease (n=68), celiac disease (n=35), suspected functional symptoms (n=23), polyposis (n=5), and miscellaneous (n=10). The overall diagnostic yield was 39%, but it was notably higher in overt bleeders, 66%, compared to 46% in the anemia group (P<0.025), 32% in the suspected Crohn's group (P<0.001), and 17% in the functional group (P<0.001). As a result of capsule endoscopy, management was altered in 26% of patients. This study shows that capsule endoscopy has both a high diagnostic yield and an impact on subsequent patient management. These data further support the role of capsule endoscopy in routine clinical practice.
Reena Sidhu; David S Sanders; Kapil Kapur; David P Hurlstone; Mark E McAlindon
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2007-03-15
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  52     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-18     Completed Date:  2007-06-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1382-6     Citation Subset:  AIM; IM    
Gastroenterology & Liver Unit, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, United Kingdom.
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MeSH Terms
Aged, 80 and over
Anemia / diagnosis*,  therapy
Capsule Endoscopy* / adverse effects
Celiac Disease / diagnosis*,  therapy
Crohn Disease / diagnosis*,  therapy
Follow-Up Studies
Gastrointestinal Hemorrhage / diagnosis*,  therapy
Gastrointestinal Neoplasms / diagnosis*,  therapy
Intestinal Polyposis / diagnosis*,  therapy
Middle Aged
Predictive Value of Tests
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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