| Capsinoids, Non-Pungent Capsaicin Analogs, Reduce Body Fat Accumulation without Weight Rebound unlike Dietary Restriction in Mice. | |
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MedLine Citation:
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PMID: 21228478 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Enhancing energy expenditure and reducing energy intake are both crucial for weight control. Capsinoids, which are non-pungent capsaicin analogs, are known to suppress body fat accumulation and reduce body weight by enhancing energy expenditure in both mice and humans. However, it is poorly understood whether the suppression of body fat accumulation by capsinoids has an advantage over dietary restriction. This study shows that the oxygen consumption was increased in mice administered with capsinoids but not in dietary-restricted mice, although there was a similar suppression of body fat accumulation in both groups. The weight rebound was more notable in the dietary-restricted mice than in the mice administered with capsinoids. These results indicate that suppressing body fat accumulation by capsinoids was more beneficial than a restricted diet for maintaining body weight. |
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Authors:
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Satoshi Haramizu; Fuminori Kawabata; Yoriko Masuda; Koichiro Ohnuki; Tatsuo Watanabe; Susumu Yazawa; Tohru Fushiki |
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Publication Detail:
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Type: Journal Article Date: 2011-01-07 |
Journal Detail:
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Title: Bioscience, biotechnology, and biochemistry Volume: 75 ISSN: 1347-6947 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
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Languages: eng Pagination: 95-9 Citation Subset: IM |
Affiliation:
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Laboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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