| Capillary permeability in septic patients. | |
| | |
MedLine Citation:
|
PMID: 6744903 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
It is suspected, but still unproven, that the increased capillary permeability which accompanies sepsis and contributes to the development of pulmonary edema (PE) involves systemic as well as pulmonary capillaries. We investigated the relationship between the colloid osmotic pressure of serum (COPS) and edema fluid (COPE) in 16 septic and 19 nonseptic patients with severe generalized edema. COPS values of septic and nonseptic patients were not significantly different (14.6 +/- 2.1 and 15.8 +/- 3.4 torr, respectively). However, the COPE of septic patients was 2.4 +/- 0.7 torr while the COPE of nonseptic patients was 1.3 +/- 0.7 torr. The COPE/COPS ratio was 0.165 in septic patients and 0.084 in nonseptic patients. Both of these differences are significant (p less than .001). It was also possible to discriminate septic from nonseptic patients on the basis of the COPE/COPS ratio. Thus, 16/17 determinations in septic patients had a ratio greater than .1, while 17/22 determinations in nonseptic patients showed a ratio less than .1. PE was present in 8/16 septic patients but in only 2/19 nonseptic patients. These data suggest that the increase in capillary permeability during sepsis is generalized. |
| | |
Authors:
|
H Ellman |
Related Documents
:
|
10612963 - Monitoring the critically ill patient. 15030963 - The relationship between leptin concentrations, the systemic inflammatory response and ... 436033 - Localization of pheochromocytoma by selective venous catheterization and assay of plasm... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Critical care medicine Volume: 12 ISSN: 0090-3493 ISO Abbreviation: Crit. Care Med. Publication Date: 1984 Aug |
Date Detail:
|
Created Date: 1984-09-04 Completed Date: 1984-09-04 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0355501 Medline TA: Crit Care Med Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 629-33 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Body Fluids / physiology Capillary Permeability* Edema / etiology, physiopathology Humans Hydrostatic Pressure Middle Aged Osmotic Pressure Pulmonary Edema / etiology, physiopathology, radiography Sepsis / blood, complications, physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Adult respiratory distress syndrome: hospital charges and outcome according to underlying disease.
Next Document: Estimation of frontal-plane cardiac vectors in heart disease.