| Capillary electrophoresis study on the dimeric SOD enzyme in the presence of ascorbic acid. | |
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MedLine Citation:
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PMID: 18386505 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A Notable decrease of the peak intensity of the capillary electrophoregram due to the dimeric SOD molecule was observed when a solution containing copper(II) chloride and ascorbic acid was added to the SOD solution, indicating that the capillary electrophoresis method is useful to detect the dissociation of the dimeric SOD molecule in solution, and that dissociation of the dimeric SOD molecule is induced by the presence of hydrogen peroxide. The present results may give reasonable countermeasures towards the sporadic amyotrophic lateral sclerosis in future. |
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Authors:
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Keita Abe; Yuzo Nishida |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Zeitschrift für Naturforschung. C, Journal of biosciences Volume: 63 ISSN: 0939-5075 ISO Abbreviation: Z. Naturforsch., C, J. Biosci. Publication Date: 2008 Jan-Feb |
Date Detail:
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Created Date: 2008-04-04 Completed Date: 2008-05-16 Revised Date: 2009-11-04 |
Medline Journal Info:
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Nlm Unique ID: 8912155 Medline TA: Z Naturforsch C Country: Germany |
Other Details:
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Languages: eng Pagination: 151-3 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Faculty of Science, Yamagata University, Yamagata 990-8560, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Ascorbic Acid / pharmacology* Cattle Dimerization Electrophoresis, Capillary / methods* Superoxide Dismutase / isolation & purification*, metabolism |
| Chemical | |
Reg. No./Substance:
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50-81-7/Ascorbic Acid; EC 1.15.1.1/Superoxide Dismutase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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