| Cannabis and cocaine: a lethal cocktail triggering coronary sudden death. | |
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MedLine Citation:
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PMID: 18402793 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The case of a 31-year-old man who died suddenly, with a history of drug abuse and no risk factors for coronary artery disease, is herein reported. Postmortem examination disclosed critical stenosis due to a fibrocellular atherosclerotic plaque complicated by occlusive thrombosis at the level of the left anterior descending coronary artery. Chemico-toxicological analysis revealed high levels of cocaine, tetrahydrocannabinol, and metabolites. When dealing with an acute coronary syndrome in young people, with or without a history of drug abuse, toxicological examination should always be performed to rule out unnatural causes of myocardial ischemia. |
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Authors:
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Massimo Montisci; Gaetano Thiene; Santo Davide Ferrara; Cristina Basso |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-07-05 |
Journal Detail:
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Title: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology Volume: 17 ISSN: 1054-8807 ISO Abbreviation: Cardiovasc. Pathol. Publication Date: 2008 Sep-Oct |
Date Detail:
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Created Date: 2008-09-08 Completed Date: 2008-10-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9212060 Medline TA: Cardiovasc Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 344-6 Citation Subset: IM |
Affiliation:
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Forensic Medicine, Department of Medico-Diagnostic Sciences and Special Therapies, University of Padua Medical School, Padua, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cannabis / adverse effects* Cocaine / adverse effects* Coronary Artery Disease / complications Coronary Stenosis / etiology Death, Sudden, Cardiac / etiology* Dopamine Uptake Inhibitors / adverse effects* Humans Male Substance-Related Disorders / physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Dopamine Uptake Inhibitors; 50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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