Document Detail


The cannabis hyperemesis syndrome characterized by persistent nausea and vomiting, abdominal pain, and compulsive bathing associated with chronic marijuana use: a report of eight cases in the United States.
MedLine Citation:
PMID:  20130993     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY METHODS: Patients were identified by the three investigators in gastroenterology clinic or inpatient wards at William Beaumont Hospital from January to August 2009 based on chronic cannabis use; otherwise unexplained refractory, recurrent vomiting; and compulsive bathing. Charts were retrospectively analyzed with follow-up data obtained from subsequent physician visits and patient interviews.
RESULTS: The eight patients on average were 32.4 ± 4.1 years old. Five were male. The mean interval between the onset of cannabis use and development of recurrent vomiting was 19.0 ± 3.7 years. Patients had a mean of 7.1 ± 4.3 emergency room visits, 5.0 ± 2.7 clinic visits, and 3.1 ± 1.9 admissions for this syndrome. All patients had visited at least one other hospital in addition to Beaumont Hospital. All patients had vomiting (mean vomiting episodes every 3.0 ± 1.7 h), compulsive bathing (mean = 5.0 ± 2.0 baths or showers/day; mean total bathing time = 5.0 ± 5.1 h/day), and abdominal pain. Seven patients took hot baths or showers, and seven patients experienced polydipsia. Four out of five patients who discontinued cannabis use recovered from the syndrome, while the other three patients who continued cannabis use, despite recommendations for cessation, continued to have this syndrome. Among those four who recovered, one patient had recurrence of vomiting and compulsive bathing with cannabis resumption.
CONCLUSIONS: Cannabis hyperemesis is characterized by otherwise unexplained recurrent nausea and vomiting, compulsive bathing, abdominal pain, and polydipsia associated with chronic cannabis use. This syndrome can occur in the United States as well as in Australia. Cannabis cessation may result in complete symptomatic recovery.
Authors:
Maria Soriano-Co; Mihaela Batke; Mitchell S Cappell
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Publication Detail:
Type:  Journal Article     Date:  2010-02-04
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  55     ISSN:  1573-2568     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-21     Completed Date:  2010-11-16     Revised Date:  2011-01-11    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3113-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, William Beaumont Hospital, 3535 W. Thirteen Mile Road, Royal Oak, MI 48073, USA.
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MeSH Terms
Descriptor/Qualifier:
Abdominal Pain / chemically induced*
Adult
Baths / psychology*
Compulsive Behavior / chemically induced*
Female
Humans
Male
Marijuana Abuse / complications*
Recurrence
Syndrome
United States
Vomiting / chemically induced*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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